The fire has caused dangerous air pollution, with fine particle pollution posing serious health risks, especially to individuals with respiratory or heart conditions, older adults, children, and pregnant people. Businesses and residents near Boyle Heights have reported disruptions, including reduced foot traffic and health-related absences. The smoke has led to breathing difficulties, irritation, and increased risks of asthma attacks and heart problems. Air quality remains a concern, particularly in East Los Angeles and downtown Los Angeles.